Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. I. Taxonomy, isolation, physico-chemical properties and biological activities.

نویسندگان

  • I Momose
  • H Iinuma
  • N Kinoshita
  • Y Momose
  • S Kunimoto
  • M Hamada
  • T Takeuchi
چکیده

New antibiotics designated decatromicins A and B were isolated from the culture broth of Actinomadura sp. MK73-NF4. They were purified by butyl acetate extraction, silica gel column chromatography, silica gel TLC and Sephadex LH-20 column chromatography. Decatromicins A and B inhibited growth of Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 52 9  شماره 

صفحات  -

تاریخ انتشار 1999